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From The Collaborative International Dictionary of English v.0.48:
Nepenthe \Ne*pen"the\, n. [Fr. Gr. ? removing all sorrow; hence, an epithet of an Egyptian drug which lulled sorrow for the day; ? not + ? sorrow, grief.] A drug used by the ancients to give relief from pain and sorrow; -- by some supposed to have been opium or hasheesh. Hence, anything soothing and comforting. [1913 Webster] Lulled with the sweet nepenthe of a court. --Pope. [1913 Webster] Quaff, O quaff this kind nepenthe. --Poe. [1913 Webster]