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From The Collaborative International Dictionary of English v.0.48:
Nihilism \Ni"hil*ism\, n. [L. nihil nothing: cf. F. nihilisme. See Annihilate.] 1. Nothingness; nihility. [1913 Webster] 2. The doctrine that nothing can be known; scepticism as to all knowledge and all reality. [1913 Webster] 3. (Politics) The theories and practices of the Nihilists. [1913 Webster]