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From The Collaborative International Dictionary of English v.0.48:
Vendetta \Ven*det"ta\, n. [It.] 1. A blood feud; private revenge for the murder of a kinsman. [1913 Webster] 2. Any feud or contention that is bitter and prolonged; however, the deep enmity may be held by only one party to the dispute; as, the former Mayor nurtured a lifelong vendetta against the candidate who defeated him. [PJC]