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From The Collaborative International Dictionary of English v.0.48:
Gnaw \Gnaw\ (n[add]), v. t. [imp. & p. p. Gnawed (n[add]d); p. pr. & vb. n. Gnawing.] [OE. gnawen, AS. gnagan; akin to D. knagen, OHG. gnagan, nagan, G. nagen, Icel. & Sw. gnaga, Dan. gnave, nage. Cf. Nag to tease.] 1. To bite, as something hard or tough, which is not readily separated or crushed; to bite off little by little, with effort; to wear or eat away by scraping or continuous biting with the teeth; to nibble at. [1913 Webster] His bones clean picked; his very bones they gnaw. --Dryden. [1913 Webster] 2. To bite in agony or rage. [1913 Webster] They gnawed their tongues for pain. --Rev. xvi. 10. [1913 Webster] 3. To corrode; to fret away; to waste. [1913 Webster] 4. To trouble in a constant manner; to plague; to worry; to vex; -- usually used with at; as, his mounting debts gnawed at him. [PJC]