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From The Collaborative International Dictionary of English v.0.48:
Irksome \Irk"some\, a. 1. Wearisome; tedious; disagreeable or troublesome by reason of long continuance or repetition; as, irksome hours; irksome tasks. [1913 Webster] For not to irksome toil, but to delight, He made us. --Milton. [1913 Webster] 2. Weary; vexed; uneasy. [Obs.] [1913 Webster] Let us therefore learn not to be irksome when God layeth his cross upon us. --Latimer. Syn: Wearisome; tedious; tiresome; vexatious; burdensome. Usage: Irksome, Wearisome, Tedious. These epithets describe things which give pain or disgust. Irksome is applied to something which disgusts by its nature or quality; as, an irksome task. Wearisome denotes that which wearies or wears us out by severe labor; as, wearisome employment. Tedious is applied to something which tires us out by the length of time occupied in its performance; as, a tedious speech. [1913 Webster] Wearisome nights are appointed to me. --Job vii. 3. [1913 Webster] Pity only on fresh objects stays, But with the tedious sight of woes decays. --Dryden. -- Irk"some*ly, adv. -- Irk"some*ness, n. [1913 Webster]