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From The Collaborative International Dictionary of English v.0.48:
Nasty \Nas"ty\ (n[.a]s"t[y^]), a. [Compar. Nastier (n[.a]s"t[i^]*[~e]r); superl. Nastiest.] [For older nasky; cf. dial. Sw. naskug, nasket.] 1. Offensively filthy; very dirty, foul, or defiled; disgusting; nauseous. [1913 Webster] 2. Hence, loosely: Offensive; disagreeable; unpropitious; wet; drizzling; as, a nasty rain, day, sky. [1913 Webster] 3. Characterized by obscenity; indecent; indelicate; gross; filthy. [1913 Webster] 4. Vicious; offensively ill-tempered; insultingly mean; spiteful; as, a nasty disposition. [PJC] 5. Difficult to deal with; troublesome; as, he fell of his bike and got a nasty bruise on his knee. [slang] [PJC] Syn: Nasty, Filthy, Foul, Dirty. Usage: Anything nasty is usually wet or damp as well as filthy or dirty, and disgusts by its stickiness or odor; but filthy and foul imply that a thing is filled or covered with offensive matter, while dirty describes it as defiled or sullied with dirt of any kind; as, filthy clothing, foul vapors, etc. [1913 Webster]