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From The Collaborative International Dictionary of English v.0.48:
Om \Om\, interj. & n. [Also Aum, Um.] [Skr. [=o]m.] A mystic syllable or ejaculation used by Hindus and Buddhists in religious rites, -- orig. among the Hindus an exclamation of assent, like Amen, then an invocation, and later a symbol of the trinity formed by Vishnu, Siva, and Brahma. Om mani padme hun, a sacred formula of buddhism (esp. of the Lamaists) translated "O, the Jewel in the Lotus, Amen," and referring to Amitabha, who is commonly represented as standing or sitting within a lotus. [Webster 1913 Suppl.]