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From The Collaborative International Dictionary of English v.0.48:
Shereef \Sher"eef\, Sherif \Sher"if\, n. [Ar. sher[imac]f noble, holy, n., a prince.] A member of an Arab princely family descended from Mohammed through his son-in-law Ali and daughter Fatima. The Grand Shereef is the governor of Mecca. [1913 Webster]