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From The Collaborative International Dictionary of English v.0.48:
Stupefaction \Stu`pe*fac"tion\, n. [Cf. F. stup['e]faction. See Stupefacient.] The act of stupefying, or the state of being stupefied. [Written also stupifaction.] [1913 Webster] Resistance of the dictates of conscience brings a hardness and stupefaction upon it. --South. [1913 Webster]